A surveillance study on the impact and effectiveness of vaccination against COVID-19 infection rates and extent of hospitalization.
Full text link: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00947-8/fulltext
Following the emergency use authorisation of the Pfizer-BioNTech mRNAA COVID-19 vaccine BNT162b2 (international non-proprietary name tozinameran) in Israel, the Ministry of Health (MoH) launched a campaign to immunise the 6·5 million residents of Israel aged 16 years and older. We estimated the real-world effectiveness of two doses of BNT162b2 against a range of SARS-CoV-2 outcomes and to evaluate the nationwide public-health impact following the widespread introduction of the vaccine.
Two doses of BNT162b2 are highly effective across all age groups (≥16 years, including older adults aged ≥85 years) in preventing symptomatic and asymptomatic SARS-CoV-2 infections and COVID-19-related hospitalisations, severe disease, and death, including those caused by the B.1.1.7 SARS-CoV-2 variant. There were marked and sustained declines in SARS-CoV-2 incidence corresponding to increasing vaccine coverage. These findings suggest that COVID-19 vaccination can help to control the pandemic.
Corroborating the high effectiveness observed, marked declines in incident cases of SARS-CoV-2 infection were observed as vaccine coverage
The primary driver of reductions in the incidence of SARS-CoV-2 infections was high vaccine coverage, not implementation of the lockdown
Even after reopenings occurred, SARS-CoV-2 incidence remained low, suggesting that high vaccine coverage might provide a sustainable path towards resuming normal activity.
1) How can we encourage people to get vaccinated amidst the stigma associated with vaccine safety and infection post-vaccination?
2) How can we help in ensuring adequate testing facilities and vaccine coverage in LMICs and rural areas?
3) How can we contribute towards awareness and dissemination of information regarding vaccination, public health measures etc. to the general population?
Vedant S Jha
HIFA profile: Vedant Shekhar Jha is a Medical Cadet at the Armed Forces Medical College Pune, India. Professional interests: Palliative care, exploring unmet needs of cancer patients, the effective communication of health awareness. He is a HIFA catalyst on the HIFA working group on Maintaining essential health services during COVID-19. https://www.hifa.org/support/members/vedant
Email address: vedantjha2000 AT gmail.com