Hello,
I am Mucheye Gizachew from Ethiopia located in East Africa.
A 2020 study conducted in Ethiopia revealed that meningitis is one of the top ten causes of death among Ethiopian infants. Group B streptococcus (GBS) has emerged as a leading cause of meningitis in neonates and young infants, resulting in high mortality. Despite this, there is no report on GBS associated meningitis in Ethiopia where infant meningitis is common.
Hence, the aim of this study was to determine the proportion of GBS associated meningitis among Ethiopian infants. PCR was prospectively used to detect GBS in culture-negative cerebrospinal fluid (CSF) samples, which were collected from infants suspected of meningitis, at Tikur Anbessa specialized hospital, Ethiopia, over a one-year period. GBS was detected by PCR in 63.9% of culture-negative CSF samples. Out of the 46 GBS positive infants, 10.9% (n = 5) of them died. The late onset of GBS (LOGBS) disease was noted to have a poor outcome with 3 LOGBS out of 5 GBS positive samples collected from patients with the outcome of death. Considering the rate of GBS positivity (GBS vs. no GBS), the probable death was assumed (10.9% (5/46) vs. 3.8% (1/26)). PCR was advantageous in the identification of GBS in culture-negative CSF samples. GBS was detected in 64% of the CSF samples from infants with meningitis compared with zero-detection rate by culture
Enhanced identification of Group B streptococcus in infants with suspected meningitis in Ethiopia
Alene Geteneh et al
PLOS One, Published: November 19, 2020
https://doi.org/10.1371/journal.pone.0242628
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0242628
Best!
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Sincerely,
Mucheye Gizachew (BSc, MSc, PhD)
Head, Department of Medical Microbiology, SBMLS, CMHS, UoG
*Associate Editor, Journal of Disability CBR & Inclusive Development*
DAAD (Germany) In-Country Scholarship Fellow
Visiting Research Scholar at CDC, Atlanta, Georgia USA
Tele: +251-0581117678; Fax:+251-0581111479; P. O. Box: 196
Mobile: 251(0)910139535
Email: muchegiza@gmail.com (muchiye888@yahoo.com)
Official (Institution) email: mucheye. <mucheye.gizachew@uog.edu.et>
WWW.uog.edu.et <http://www.uog.edu.et/> <http://www.uog.edu.et/>
gizachew@uog.edu.et <mucheye.gizachew@uog.edu.et>*n*=1456; *h-index**=*21;
& *i10-inde**x*=27
*LinkedIn:* *https://www.linkedin.com/in/mucheye-gizachew-9a754b4a
<https://www.linkedin.com/public-profile/settings/>; **ORCID ID:*
https://orcid.org/ <https://orcid.org/0000-0002-3754-2618>
*0000-0002-3754-2618*
Research / Citation Metrics: *Citatio*00-0002-3754-2618
<https://orcid.org/0000-0002-3754-2618>
Scopus Author ID: 55123088900
<http://www.scopus.com/inward/authorDetails.url?authorID=55123088900&part...
Web of Science Researcher ID: MVU-5532-2025.
*ሥዓት** ጊዜን ያሳይሃል፡ ጊዜ ደግሞ ሰዎችን (ህዝብ)*
HIFA profile: Mucheye Gizachew Beza is an instructor, researcher and community service provider at the University of Gondar, Ethiopia. By profession, he is a Medical Microbiologist with academic backgrounds in Nursing and Biological Sciences. His professional and research interests focus on Group B Streptococcus (GBS), maternal and neonatal infectious disease prevention, antimicrobial resistance (AMR) focusing on One Health Approach, public health microbiology, biosafety and biosecurity, disease surveillance, and health education. He is particularly committed to advancing community awareness, strengthening public health interventions, and promoting evidence-based strategies to improve maternal and child health outcomes. His work aims to bridge research, education, and public health practice to address emerging infectious disease challenges and enhance healthcare quality and safety. Email address: muchegiza AT gmail.com